Anesthetic consideration of Niemann-Pick Disease type C

A known case of NPC1 requiring anesthesia for Percutaneous Endoscopic Gastrostomy is presented and a brief review about molecular basis and recent advances in this field is reviewed. Nieman-Pick disease type C is a rare, autosomal recessive, neurometabolic disorder associated with the accumulation of unesterified cholesterol in lysosomes and late endosomes. Because of multiple organ involvement and wide range of clinical manifestations, these patients will demand multiple diagnostic and therapeutic procedures requiring anesthesia. Sincepathogenesis of this disease is still unknown, further investigations on cellular and molecular basis of NPC is needed. In this report we present a known case of NPC1 requiring anesthesia for Percutaneous Endoscopic Gastrostomy and a brief review about molecular basis and recent advances in this field.

Niemann-Pick Disease Concise Medical Knowledge

Changes in Caries Risk and Activity of a 9-Year-Old Patient with

Niemann-Pick disease type C

Anesthetic complications during general anesthesia without

5 Most Promising Companies offering hope to patients with Niemann

Anesthetic management of pediatric patients with Niemann‐Pick

Anesthetic consideration of Niemann-Pick Disease type C

PDF) Dental Treatment of Two Children with Niemann Pick Disease

Gene Therapy in a Mouse Model of Niemann–Pick Disease Type C1

Niemann-Pick disease type C

Niemann Pick Disease Type C - Symptoms, Causes, Treatment

Consensus clinical management guidelines for Niemann-Pick disease