A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
Por um escritor misterioso
Last updated 24 fevereiro 2025
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…
MLL::AF9 degradation induces rapid changes in transcriptional
PDF) Development of an orally bioavailable selective inhibitor of
Paralog-specific signaling by IRAK1/4 maintains MyD88-independent
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
Evolving insights on histone methylome regulation in human acute
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
Therapeutic implications of menin inhibition in acute leukemias
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
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