Metabolite Toxicity as a Driver of Aging and Disease — THE HUGHES LAB

Metabolite Toxicity as a Driver of Aging and Disease

Mitochondrial-derived compartments facilitate cellular adaptation to amino acid stress - ScienceDirect

Adipaging': ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue - Pérez - 2016 - The Journal of Physiology - Wiley Online Library

Research Overview — THE HUGHES LAB

The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models - ScienceDirect

Toxicity of Tetrabromobisphenol A and Its Derivative in the Mouse Liver Following Oral Exposure at Environmentally Relevant Levels

How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction

Frontiers The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration

IJMS, Free Full-Text

Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed